# MatriChem — Full Product Catalog Site: https://www.matrichem.com Generated: 2026-07-03T01:34:58.072Z --- # Collagen Type I > Bovine Achilles tendon-derived type I collagen **Company:** MatriChem **Canonical URL:** https://www.matrichem.com/products/collagen-type-i **Last updated:** 2026-05-16T22:27:46.176129+00:00 **Availability:** Available **Price:** Request quote **Category:** consumable ## Intended Use ## Collagen Type I Collagen is the most abundant protein in mammals, accounting for approximately one-third of the total protein in the human body. Collagens are found in tissues such as skin, bone, ligaments, tendons, cartilage and the cornea. Collagens mostly have a structural function but they are also responsible for conveying critical biochemical cues to cells. ## MatriChem's Collagen Type I **MatriChem's collagen is bovine Achilles tendon-derived type I collagen.** MatriChem ensures consistent collagen properties by sourcing the tendons from cattle with controlled age, breed, sex, diet, and amount of exercise. This is enabled by the fact that **MatriChem operates the first laboratory certified by the Bulgarian Food Safety Agency (BFSA)** to process animal byproducts for research purposes — specifically for the extraction of collagen and other extracellular matrix (ECM) biomolecules. The purity of MatriChem's collagen type I has been ascertained by Coomassie-stained SDS-PAGE, differential scanning calorimetry, and Biuret protein assay. Its solubility in acetic acid has been established to be comparable to or even better than commercially available bovine collagen type I. ## Bioprinting Formulation **We have developed a collagen bioink formulation suitable for extrusion bioprinting.** The formulation is insensitive to a temperature as high as 20°C within the typical duration of a bioprinting process, making it suitable for use with a cooled bioprinting head. The bioink is thermally crosslinked at carefully selected bed temperature. ## Details [EMAIL TO ORDER](mailto:office@matrichem.com) ![Image description](https://xlccwnhdusmvvaftmmyk.supabase.co/storage/v1/object/public/content-images/pages/1772075591996.webp) **Collagen is the most abundant protein in mammals, accounting for approximately one-third of the total protein in the human body.** In fact, collagen is a superfamily of proteins consisting of at least 46 types of polypeptide chains that make up the 28 types of collagen molecules known thus far in vertebrates. **Collagens are found in tissues such as skin, bone, ligaments, tendons, cartilage and the cornea.** All collagens exhibit a unifying feature that classifies molecules as belonging to the collagen family, namely a repeating Gly-X-Y motif (wherein Gly is glycine while X and Y may be any amino acid, but most frequent are proline and 4-hydroxyproline, respectively). **Collagens mostly have a structural function but they are also responsible for conveying critical biochemical cues to cells.** At a cellular level, functions such as cell adhesion, migration, metabolism, and proliferation are all regulated by cues provided by collagen. It has been widely explored to repair the human body, e.g. for wound healing. **MatriChem’s collagen is bovine Achilles tendon-derived type I collagen.** MatriChem ensures consistent collagen properties by sourcing the tendons from cattle with controlled age, breed, sex, diet, and amount of exercise. This is enabled by the fact that **MatriChem operates the first laboratory certified by the Bulgarian Food Safety Agency (BFSA)** to process animal byproducts for research purposes, specifically, for the extraction of collagen and other extracellular matrix (ECM) biomolecules. The purity of MatriChem’s collagen type I has been ascertained by Coomassie-stained SDS-PAGE, differential scanning calorimetry, and Biuret protein assay. Furthermore, based on turbidity measurements, **its solubility in acetic acid has been established to be comparable to or even better than commercially available bovine collagen type I.** ![Image description](https://xlccwnhdusmvvaftmmyk.supabase.co/storage/v1/object/public/content-images/pages/1772349772087.webp) ![Image description](https://xlccwnhdusmvvaftmmyk.supabase.co/storage/v1/object/public/content-images/pages/1772349852475.webp) **We have established the kinetics of the collagen fibrillogenesis, monitored at various temperature ramp rates, to be the most sensitive indicator of the quality of the collagen batch.** During our development of the extraction procedure, qualitatively different gelation kinetics were observed for collagen batches which demonstrated no other significant differences in the monitored properties. ![Image description](https://xlccwnhdusmvvaftmmyk.supabase.co/storage/v1/object/public/content-images/pages/1772075993260.webp) **We have developed a collagen bioink formulation suitable for extrusion bioprinting.** The formulation is insensitive to a temperature as high as 20°C within the typical duration of a bioprinting process. This makes it suitable for use with a cooled bioprinting head in the absence of a temperature-controlled head. The bioink is thermally crosslinked at carefully selected bed temperature. ![Image description](https://xlccwnhdusmvvaftmmyk.supabase.co/storage/v1/object/public/content-images/pages/1772164018216.gif) [EMAIL TO ORDER](mailto:office@matrichem.com) ## How to Order Email **office@matrichem.com** with subject `Order Inquiry - Collagen Type I` --- Source: https://www.matrichem.com/products/collagen-type-i --- # GelMA > Methacrylated gelatin for tissue engineering by extrusion bioprinting **Company:** MatriChem **Canonical URL:** https://www.matrichem.com/products/gelma **Last updated:** 2026-05-16T22:34:37.852021+00:00 **Availability:** Available **Price:** Request quote **Category:** consumable ## Intended Use ## GelMA (Methacrylated Gelatin) GelMA is one of the most popular biomaterials employed in tissue engineering by extrusion bioprinting. GelMA is a gelatin derivative in which a major limitation of the otherwise inherently biocompatible and biodegradable gelatin is addressed — it is insensitive to physiological temperature. Gelatin is a hydrolysate of collagen with significantly lower immunogenicity but it still contains the arginine-glycine-aspartic acid (RGD) peptide sequence, required for cell adhesion, proliferation, and differentiation, and a matrix metalloproteinase (MMP) degradation sequence which promotes cell enzymatic degradation. ## Various Degrees of Methacrylation GelMA enables diverse applications since the physico-chemical properties of its hydrogels can be tuned by adjusting its degree of methacrylation, tailoring its gelling behavior, solution viscosity, and mechanical strength. The latter is rather important since different natural tissues respond differently to mechanical stresses, and the ideal material intended for the creation of a tissue model would closely match the mechanical properties of the target tissue. ## Characteristics We have developed a reproducible procedure for the methacrylation of gelatin. We are currently establishing the control limits for the gelatin methacrylation SOP. MatriChem's GelMA hydrogels are covalently crosslinked by visible light, reducing the negative impact on cell survival when compared to the typical UV crosslinking. MatriChem's SOP for gelatin methacrylation enables us to maintain the variability of the degree of methacrylation as low as ±5%. ## Details [EMAIL TO ORDER](mailto:office@matrichem.com) ### GelMA (Methacrylated gelatin)… GelMA is one of the most popular biomaterials employed in tissue engineering by extrusion bioprinting. GelMA is a gelatin derivative in which a major limitation of the otherwise inherently biocompatible and biodegradable gelatin is addressed, i.e. it is insensitive to physiological temperature. Gelatin is a hydrolysate of collagen with significantly lower immunogenicity but it still contains the arginine-glycine-aspartic acid (RGD) peptide sequence, required for cell adhesion, proliferation, and differentiation, and a matrix metalloproteinase (MMP) degradation sequence which promotes cell enzymatic degradation. ### …with various degrees of methacrylation GelMA enables diverse applications since the physico-chemical properties of its hydrogels can be tuned by adjusting its degree of methacrylation, tailoring its gelling behavior, solution viscosity, and mechanical strength. The latter is rather important since different natural tissues respond differently to mechanical stresses, and the ideal material intended for the creation of a tissue model would closely match the mechanical properties of the target tissue. ![1H NMR spectra of gelatin and GelMA with two different degrees of methacrylation](https://images.squarespace-cdn.com/content/v1/616f08846eb3b504cfe861ad/1634666635047-SCXVMG7VX6ROKG9EJYAT/GelMA_25-75_NMR.png) ***1H NMR spectra** Proton NMR spectra of gelatin and GelMA with two different degrees of methacrylation.* ### Characteristics We have developed a reproducible procedure for the methacrylation of gelatin. We are currently establishing the control limits for the gelatin methacrylation SOP. MatriChem's GelMA hydrogels are covalently crosslinked by visible light reducing the negative impact on cell survival when compared to the typical UV crosslinking. ![GelMA Control Charts showing degree of methacrylation variability](https://images.squarespace-cdn.com/content/v1/616f08846eb3b504cfe861ad/d80b3bdd-cfa2-47c8-8014-3771841136c6/GelMA+-+Control+Chart_updated.png) **Control Charts** MatriChem's SOP for gelatin methacrylation enables us to maintain the variability of the degree of methacrylation as low as ±5%. ### Place your order today! [EMAIL TO ORDER](mailto:office@matrichem.com) ## How to Order Email **office@matrichem.com** with subject `Order Inquiry - GelMA` --- Source: https://www.matrichem.com/products/gelma --- # Ultrasound Breast Phantom > Realistic ultrasound breast phantom for sonography and biopsy training **Company:** MatriChem **Canonical URL:** https://www.matrichem.com/products/ultrasound-breast-phantom **Last updated:** 2026-05-09T20:42:23.533369+00:00 **Availability:** Available **Price:** EUR 249 **Category:** phantom ## Intended Use ## Ultrasound Breast Phantom for Medical Training Our ultrasound breast phantom is designed for realistic sonography and biopsy training, mimicking the acoustic properties of human breast tissue and common lesions such as cysts, fibroadenomas, and cancers. Developed in partnership with **The Bulgarian Breast Cancer Association**, it supports high-quality, standardized education for radiologists and clinicians. ## Key Features - Realistic ultrasound imaging with tissue-mimicking acoustic properties - Includes common lesions: cysts, fibroadenomas, and tumors (benign & malignant) - Suitable for ultrasound-guided biopsy training and needle insertion practice - Durable gel-based construction designed for repeated procedures - Available in multiple configurations depending on course size & training needs ## Technical Specifications **Phantom material:** Tissue-mimicking hydrogel - **Acoustic properties:** - Speed of sound: ~1520 m/s - Attenuation coefficient: ~0.30 dB/cm/MHz - Density: ~1.02 g/cm³ - **Lesion types included:** Anechoic oval cyst, Hypoechoic oval fibroadenoma, Irregular cancerous masses - **Lesion sizes:** 15–30 mm - **Phantom dimensions:** 140 mm × 140 mm × 70 mm - **Compatible imaging modalities:** Ultrasound (5–15 MHz probes) - **Biopsy capability:** Supports needle insertions, Self-healing - **Durability:** Withstands ~50–100 needle passes ## Benefits for Training & Education **Realistic ultrasound simulation** — The phantom provides tissue-mimicking acoustic properties that closely resemble human breast tissue, enabling trainees to practice probe handling, lesion localization, and depth assessment. **Safe and Effective Biopsy Training** — Designed for ultrasound-guided interventions, the phantom allows trainees to perform needle insertion and targeting exercises without risk to patients. **Standardized Learning for Groups** — Because every phantom contains the same lesion types and image characteristics, training programs can ensure consistent learning outcomes across large groups. ## How to Choose Phantoms for Your Course **For courses of 12 to 20 students:** Minimum six breast phantoms — starting at €1,410 **For courses of 21 to 50 students:** Minimum 12 breast phantoms — starting at €2,628 **For single phantom:** €249 ## Details [EMAIL TO ORDER](mailto:office@matrichem.com) Our ultrasound breast phantom is designed for realistic sonography and biopsy training, mimicking the acoustic properties of human breast tissue and common lesions such as cysts, fibroadenomas, and cancers. Developed in partnership with [**The Bulgarian Breast Cancer Association**](https://bbca.bg/), it supports high-quality, standardized education for radiologists and clinicians. ### Key Features - Realistic ultrasound imaging with tissue-mimicking acoustic properties - Includes common lesions: cysts, fibroadenomas, and tumors (benign & malignant) - Suitable for ultrasound-guided biopsy training and needle insertion practice - Durable gel-based construction designed for repeated procedures - Available in multiple configurations depending on course size & training needs ![Ultrasound breast phantom for core biopsy training](https://images.squarespace-cdn.com/content/v1/616f08846eb3b504cfe861ad/1764499134791-SCZVPIP6D9R4Z75TN7VQ/ultrasound-breast-phantom-core-biopsy.jpg) ### Technical Specifications **Phantom material:** Tissue-mimicking hydrogel - **Acoustic properties:** - Speed of sound: ~1520 m/s - Attenuation coefficient: ~0.30 dB/cm/MHz - Density: ~1.02 g/cm³ - **Lesion types included:** - Anechoic oval cyst - Hypoechoic oval fibroadenoma - Irregular cancerous masses - **Lesion sizes:** 15–30 mm - **Phantom dimensions:** 140 mm × 140 mm × 70 mm - **Compatible imaging modalities:** - Ultrasound (5–15 MHz probes) - **Biopsy capability:** - Supports needle insertions - Self-healing - **Durability:** - Withstands ~50–100 needle passes ![Ultrasound image of phantom with core needle](https://images.squarespace-cdn.com/content/v1/616f08846eb3b504cfe861ad/477842ec-b721-4b49-9092-f42ef15469ed/echograph-cancer-core-biopsy.jpg) ![Ultrasound image of phantom with core needle](https://images.squarespace-cdn.com/content/v1/616f08846eb3b504cfe861ad/1764499134145-BZSSXY4PF0ZMETVZ0KUO/Breast-phantom-core-needle-ultrasound.png) ### Benefits for Training & Education The use of tissue-like phantoms is important for education of medical specialists for various reasons: ### Realistic ultrasound simulation The phantom provides tissue-mimicking acoustic properties that closely resemble human breast tissue, enabling trainees to practice probe handling, lesion localization, and depth assessment. Consistent lesion appearance across sessions allows learners to build confidence with reliable, repeatable images. ### Safe and Effective Biopsy Training Designed for ultrasound-guided interventions, the phantom allows trainees to perform needle insertion and targeting exercises without risk to patients. Internal structures respond realistically during biopsy practice, helping learners develop accurate hand–eye coordination and improve procedural proficiency. ### Standardized Learning for Groups Because every phantom contains the same lesion types and image characteristics, training programs can ensure consistent learning outcomes across large groups. This supports objective skills assessment, efficient teaching in workshops or courses, and enables repeated practice in a controlled environment. - **** - **** - **** ### Types of Breast Phantom Lesions ### Cyst Anechoic, fluid-filled cysts appear as black circular structures under ultrasound. Our phantom reproduces their distinct deformation during needle insertion. ### Fibroadenoma Smooth, oval, hypoechoic masses that closely match the appearance of real fibroadenomas. Ideal for practicing lesion localization and depth assessment. Colored distinctly to help identify successful biopsy. ### Cancer Irregular, hypoechoic structures that mimic malignant tumors. Designed to train pattern recognition and biopsy targeting of suspicious lesions. Colored distinctly to help identify successful biopsy. ### How to choose phantoms for your course ### For courses of 12 to 20 students Minimum six breast phantoms with three lesions (cyst, fibroadenoma, and cancer) each **Time to deliver**: 2-3 weeks **Price**: starting at 1,410 EUR ### For courses of 21 to 50 students Minimum 12 breast phantoms with three lesions (cyst, fibroadenoma, and cancer) each **Time to deliver**: 3-4 weeks **Price**: starting at 2,628 EUR Phantoms are an indispensable tool in ultrasound/sonography training as they provide a realistic, safe, and repeatable environment for acquiring essential skills necessary for accurate diagnosis and effective treatment. - **** - **** ### Order Breast Phantoms Interested in ordering breast phantoms for your training course? Get in touch with us to discuss your requirements and receive a custom quote. [EMAIL TO ORDER](mailto:office@matrichem.com) ## How to Order Email **office@matrichem.com** with subject `Order Inquiry - Ultrasound Breast Phantom` --- Source: https://www.matrichem.com/products/ultrasound-breast-phantom --- # Cytoink — Bioinks, Biomaterials & 3D Bioprinting > Bioinks, biomaterials, and 3D bioprinting products from Cytoink — GelMA, SilMA, ready-to-use bioinks, and photoinitiators. **Company:** MatriChem **Canonical URL:** https://www.matrichem.com/products/cytoink **Last updated:** 2026-04-23T03:31:38.730114+00:00 **Availability:** Available **Price:** Request quote **Partner:** Cytoink **Category:** other ## Details [EMAIL TO ORDER](mailto:office@matrichem.com) ### GelMA Biomaterials Cell-supportive materials to enable functional mimicry of human tissues. | Product | Price (5g) | Price (20g) Popular | Price (50g) | Bioprinting | |---|---|---|---|---| | **Porcine (300 bloom)** | **$375** ($75/g) | **$1,400** ($70/g) | **$3,200** ($64/g) | DLP, Extrusion, Fresh | | **Porcine (175 bloom)** | **$375** ($75/g) | **$1,400** ($70/g) | **$3,200** ($64/g) | DLP, Extrusion, Fresh | | **Bovine (225 bloom)** | **$375** ($75/g) | **$1,400** ($70/g) | **$3,200** ($64/g) | DLP, Extrusion, Fresh | | **Fish (Warm water)** | **$375** ($75/g) | **$1,400** ($70/g) | **$3,200** ($64/g) | DLP, Extrusion, Fresh | | **Fish (Cold water)** | **$375** ($75/g) | **$1,400** ($70/g) | **$3,200** ($64/g) | DLP, Fresh | ### SilMA Biomaterials Silk-based materials for advanced tissue engineering and regenerative applications. | Product | Price (5g) | Price (20g) Popular | Price (50g) | Bioprinting | |---|---|---|---|---| | **SilMA (Silk Methacrylate)** | **$1,300** ($260/g) | **$4,800** ($240/g) | **$11,000** ($220/g) | DLP, Extrusion, Fresh | ### Ready-to-Use Bioinks 100+ basal formulations for in vitro 3D tissue scaffold fabrication, extrusion & DLP bioprinting. | Product | Price (50ml) | Price (200ml) Popular | Price (500ml) | Bioprinting | |---|---|---|---|---| | **Any Gelatin Source & Formulation** | **$550** ($110/10ml) | **$2,000** ($100/10ml) | **$4,500** ($90/10ml) | DLP, Extrusion, Fresh | ### Training Bioinks Cost-effective options for learning and testing bioprinting techniques. | Product | Price (100ml) | Bioprinting | |---|---|---| | **DLP Bioink (10-20% PEGDA500)** | **$330** ($33/10ml) | DLP | | **Extrusion Bioink 1 (Pluronic)** | **$330** ($33/10ml) | Extrusion | | **Extrusion Bioink 2 (Alginate)** | **$330** ($33/10ml) | Extrusion | [EMAIL TO ORDER](mailto:office@matrichem.com) ## How to Order Email **office@matrichem.com** with subject `Order Inquiry - Cytoink — Bioinks, Biomaterials & 3D Bioprinting` --- Source: https://www.matrichem.com/products/cytoink